Group paper accepted for publication in PLoS Computational Biology and for presentation at RECOMB 2014

Our group manuscript, entitled “An integrated model of multiple-condition ChIP-seq data reveals predeterminants of Cdx2 binding”, has been accepted for publication. The manuscript will be presented at the RECOMB 2014 conference, which will be held in Pittsburgh this year from April 2nd – 5th. As part of the conference submission, the manuscript was also reviewed…

Co-authored paper published in Stem Cell Reports

A paper on which we¬†collaborated with Elizabeth Paik and her colleagues in Len Zon’s lab at Harvard University has been published in Stem Cell Reports. The paper, entitled “A Cdx4-Sall4 Regulatory Module Controls the Transition from Mesoderm Formation to Embryonic Hematopoiesis“, examined the functions of Cdx4 and Sall4 during the initiation of zebrafish¬†hematopoiesis using ChIP-seq,…

Two papers published in Nature Neuroscience

Two papers which Shaun jointly first-authored with Esteban Mazzoni have been published in the same issue of Nature Neuroscience. In “Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity“, we describe the mechanism behind the combinatorial action of transcription factors in motor neuron programming. Specifically, we found that Isl1 cooperates with Phox2a…